By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 10 February 2023 Tomas Roos defends his thesis 17 February 2023. The aggregation of the protein Amyloid-beta (Abeta) into plaques outside the nerve cells has been recognized in patients with Alzheimer’s disease since 1905. But eliminating the plaques has not helped patients so far. Still, Tomas Roos thinks that Abe

https://www.multipark.lu.se/article/does-alzheimers-disease-start-inside-neurons-phd-interview-tomas-roos - 2025-04-25

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 28 February 2023 The milestone transplant was performed at Skåne University Hospital in February. On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at Skåne University Hospital, Sweden. The product has been developed by Lund University and it is now being tested in

https://www.multipark.lu.se/article/first-patient-receives-milestone-stem-cell-based-transplant-parkinsons-disease - 2025-04-25

By press [at] liu [dot] se (Mikael Sönne) - published 8 March 2023 With the injectable gel the researchers were able to grow electrodes in living tissue. Here it is tested on a microfabricated circuit. Photo: Thor Balkhed/Linköpings universitet The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully

https://www.multipark.lu.se/article/electrodes-grown-brain - 2025-04-25

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 20 March 2023 Kajsa Brolin defends her thesis 27 March 2023. Photo: Kennet Ruona Kajsa Brolin explores how our genes and environment affect the risk of developing Parkinson’s disease. March 27, she defends her Ph.D. project partly based on MultiPark’s biobank sample collection. Here, she tells about the newly disco

https://www.multipark.lu.se/article/genes-and-environment-pd-phd-interview-kajsa-brolin - 2025-04-25

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 13 March 2023 After a decade of protocol development and preparations, MultiPark researchers have finally launched the clinical trial. Recently, dopamine-producing cells generated from embryonic stem cells were transplanted into the first Parkinson's patient at Skåne University Hospital. During the autumn 2022, the

https://www.multipark.lu.se/article/stem-pd-bench-bedside-story-multipark-researchers-0 - 2025-04-25

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 16 March 2023 Looking for the next step in your career? In need of some scientific inspiration? Or are you just curious about what MultiPark´s senior researchers are doing and their professional journey? Listen to MultiPark’s new podcast series “Meet our scientists”! In a newly launched podcast, young MultiPark res

https://www.multipark.lu.se/article/meet-our-scientists-new-podcast-young-multipark-researchers - 2025-04-25

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 11 April 2023 Behind the ongoing clinical trials are years of basic research in the lab where the new generation of researchers continues where the previous one handed over. Photo: Kenneth Ruona. In the early 1950s, no one knew what caused Parkinson's disease. Then, Arvid Carlsson's discovery of dopamine opened the

https://www.multipark.lu.se/article/world-parkinsons-day-transplantations-parkinsons-disease-time-travel - 2025-04-25

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 28 March 2023 Genetics are one of the keys to understanding neurodegenerative disease. That is why MultiPark researchers with expertise in genetics gather across research groups. Genetics of neurodegenerative diseases is a new special interest group (SIG) addressing scientific and technological needs to unravel the

https://www.multipark.lu.se/article/genetics-neurodegenerative-diseases-special-interest-group - 2025-04-25

By katrin [dot] stahl [at] med [dot] lu [dot] se (Lund University) - published 13 April 2023 Sara Linse and Oskar Hansson. Three researchers at Lund University, all with a long list of significant research credentials, have been awarded the ERC Advanced Grant worth EUR 2.5 million each to further develop and advance their research projects. Two of them are MultiPark research leaders. They do resea

https://www.multipark.lu.se/article/double-success-multipark-research-groups-prestigious-eu-grant-round - 2025-04-25

By asa [dot] hansdotter [at] med [dot] lu [dot] se (Åsa Hansdotter) - published 17 May 2023 Several Nobel laureates, renowned scientists, and successful biotech entrepreneurs are coming to Lund in May to participate in the Lund Spring Symposium, an international pharmaceutical symposium sponsored by MultiPark. Sarah Tabrizi, a high profile Huntington researcher, and some of MultiPark's own researc

https://www.multipark.lu.se/article/superstars-coming-lund-pharmaceutical-symposium-sponsored-multipark - 2025-04-25

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 29 May 2023 A 7 Tesla MRI of a human brain. Picture: Tekla Kylkilahti, Lundgaard group. Recent studies indicate that acquired brain injuries, such as traumatic brain injury, trigger potentially harmful responses that may lead to neurodegenerative pathology. “Acquired brain injuries and their links to neurodegenerat

https://www.multipark.lu.se/article/acquired-brain-injuries-special-interest-group - 2025-04-25

Published 23 February 2021 Gesine Paul-Visse, Associate Professor and last author of the study. Overexpression of the Parkinson-related protein, α-synuclein, leads to blood-brain barrier leakage and pericyte activation in mice. A study published in Scientific Reports identifies pericytes as potential target cells for early interventions. Parkinson’s disease is a movement disorder caused by the acc

https://www.multipark.lu.se/article/pericytes-link-between-parkinson-related-protein-and-blood-brain-barrier-disruption - 2025-04-25

Published 11 March 2021 A high power microscopy image of a neuron (blue) in which the epigenetic silencing of ERVs are lost, resulting in abundant ERV proteins (red). Photo credit: Marie Jönsson. Researchers from Lund Stem Cell Center highlight the importance of controlling viral elements that reside in the genome and how their activation during development may contribute to brain disorders later

https://www.multipark.lu.se/article/activation-ancient-viruses-during-brain-development-causes-inflammation - 2025-04-25

By alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 9 March 2021 Shelby Shrigley defends her PhD thesis on Friday 12th March 2021. During her PhD studies Shelby Shrigley has been exploring patient-specific cell replacement therapy for Parkinson's disease. Defending her PhD thesis on March 12th, here Shelby tells us about her research within the Developmental and Regen

https://www.multipark.lu.se/article/phd-defence-interview-shelby-shrigley - 2025-04-25

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 25 March 2021 Ruben Smith is responsible for brain imaging in the study recently discovering that the Alzheimer’s-related protein tau accumulates faster in women compared to men. Alzheimer’s disease seems to progress faster in women than in men. The protein tau accumulates at a higher rate in women, according to re

https://www.multipark.lu.se/article/women-accumulate-alzheimers-related-protein-faster - 2025-04-25

By alexander [dot] doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 23 March 2021 Immunofluorescence image of toxic alpha-synuclein aggregates (green) accumulating in astrocytes (purple). The nuclei of the cells are shown in blue. Credit: Laurent Roybon. In a collaborative study, with other European research groups, scientists from Lund University in Sweden have shed new light on how

https://www.multipark.lu.se/article/new-insights-toxic-protein-aggregate-formation-parkinsons-disease-size-matters - 2025-04-25

By Martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 8 April 2021 On the last of December, Professor Gunnar Gouras left his position as a coordinator for MultiPark after five years. Here is how he sums up his time and mission for our environment. Can you describe your time as a coordinator for Multipark? To lead Multipark has been very interesting as well as challeng

https://www.multipark.lu.se/article/interview-gunnar-gouras-about-his-time-coordinator - 2025-04-25

By Alexander [dot] Doyle [at] med [dot] lu [dot] se (Alexander Doyle) - published 12 April 2021 Prof. Malin Parmar (right) with researcher Tiago Cardoso (left). Photo credit: Kennet Ruona. Congratulations to Prof. Malin Parmar, who has been elected as one of three new members of the Board of Directors at the International Society for Stem Cell Research (ISSCR). The Developmental and Regenerative N

https://www.multipark.lu.se/article/malin-parmar-elected-isscr-board-directors - 2025-04-25

By tove [dot] gilvad [at] med [dot] lu [dot] se (Tove Gilvad) - published 29 April 2021 Tau accumulation in different brain regions depending on the subtype of Alzheimer’s disease. Photo: J Vogel Alzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can now show how tau spreads according to four distinct patterns that l

https://www.multipark.lu.se/article/alzheimers-disease-composed-four-distinct-subtypes - 2025-04-25

By martina [dot] svensson [at] med [dot] lu [dot] se (Martina Svensson) - published 3 May 2021 On May 11, it is time for the first of a total of six workshops concerning the strategic research areas’ (SRA) work on sustainable development. Sustainability is more than climate and environmental issues. Goal number 3 of the UN global sustainability goals focuses on “good health and well-being”. The wo

https://www.multipark.lu.se/article/workshop-series-sustainability-effect-research - 2025-04-25